RNA INTERFERENCE TARGETING NOX4 PROTECTS VISUAL FUNCTION IN AN EXPERIMENTAL MODEL OF RETINAL DETACHMENT BY ALLEVIATING BLOOD-RETINAL BARRIER DAMAGE

RNA interference targeting NOX4 protects visual function in an experimental model of retinal detachment by alleviating blood-retinal barrier damage

AIM: To observe the effects of the inhibition of NADPH oxidase 4 (NOX4) expression on the retinal vascular barriers and visual function after retinal detachment (RD).METHODS: RD model was established 3wk after adeno-associaned virus vector injection.The retinal tissue was harvested 3d after RD, and the death of retinal vascular endothelial cells an

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Appraisal of arid land status: a holistic assessment pertains to bio-physical indicators and ecosystem values

Abstract Background Appraisal of arid land status is very crucial one to know the extent and factors associated with their degradation.Previous studies from arid regions are mostly qualitative in nature (indicator assessment like good, moderate, severe, and very severe) and generally overlooked the significance of temporal fluctuation.Methods In th

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The Interface between Fungal Biofilms and Innate Immunity

Fungal biofilms are communities of adherent cells surrounded by an extracellular matrix.These biofilms are commonly found during infection caused by a variety of fungal pathogens.Clinically, biofilm infections can be extremely difficult to eradicate due to their resistance to antifungals and host defenses.Biofilm formation can protect fungal pathog

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The instant effect of embodiment via mirror visual feedback on electroencephalogram-based brain connectivity changes: A pilot study

The therapeutic efficacy of mirror visual feedback (MVF) is attributed to the perception of embodiment.This study intends to investigate the instantaneous effect of embodiment Crimp lugs and terminals on brain connectivity.Twelve healthy subjects were required to clench and open their non-dominant hands and keep the dominant hands still during two

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